Brain Perfusion Correlates of Apathy in Alzheimer's Disease
نویسندگان
چکیده
منابع مشابه
Structural correlates of apathy in Alzheimer's disease.
BACKGROUND Apathy is the most common noncognitive symptom in Alzheimer's disease (AD). The structural correlates of apathy in AD have not yet been described. METHODS We analyzed magnetic resonance imaging data of 35 AD patients with and without apathy. RESULTS There was a significant linear association between apathy severity and cortical gray matter atrophy in the bilateral anterior cingul...
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BACKGROUND Apathy is the most common neuropsychiatric manifestation in Alzheimer disease (AD). Clinical, single-photon emission computed tomography, magnetic resonance imaging, and pathologic studies of apathy in AD have suggested an association with frontal dysfunction, most supportive of anterior cingulate abnormalities, but without a definitive localization. OBJECTIVE To examine the associ...
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BACKGROUND Apathy is a pervasive noncognitive neuropsychiatric disturbance in Alzheimer disease, which causes significant caregiver distress. The neuroanatomical substrate of apathy is not well understood. OBJECTIVE To study the relationship between regional cerebral blood flow and the presence and severity of the personality disturbance, apathy, in individuals with Alzheimer disease. DESIG...
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Parkinson's disease (PD) is associated with various nonmotor symptoms including neuropsychiatric and cognitive dysfunction. We examined the relation between apathy, anxiety, side of onset of motor symptoms, and cognition in PD. We hypothesized that PD patients would show different neuropsychiatric and neurocognitive profiles depending on the side of onset. 22 nondemented PD patients (11 right-s...
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Non-motor symptoms such as neuropsychiatric and cognitive dysfunction have been found to be common in Parkinson's disease (PD) but the relation between such symptoms is poorly understood. We focused on alexithymia, an impairment of affective and cognitive emotional processing, as there is evidence for its interaction with cognition in other disorders. Twenty-two non-demented PD patients and 22 ...
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ژورنال
عنوان ژورنال: Dementia and Neurocognitive Disorders
سال: 2018
ISSN: 1738-1495,2384-0757
DOI: 10.12779/dnd.2018.17.2.50